ADME WorkBench is a versatile software application providing flexible, robust pharmacokinetic modeling by integrating state-of-the-art absorption, distribution, metabolism and excretion methods. Designed for research applications in toxicology, pharmacology and biotechnology, ADME WorkBench supports pharmacokinetic prediction from in vitro and/or in vivo data for drugs and environmental chemicals. The ADME WorkBench user interface offers a highly optimized workflow for predictive pharmacokinetics, while allowing ample flexibility to adapt to specific research needs. The pharmacokinetic models used in ADME WorkBench are based on research resulting from the PhRMA CPCDC Initiative on Predictive Models of Human Pharmacokinetics, and described in a series of articles published in the Journal of Pharmaceutical Sciences in 2011. Extension of the models and implementation in ADME WorkBench has resulted from an ongoing scientific collaboration between Dr. Patrick Poulin and AEgis Technologies.
ADME WorkBench assembles a number of state-of-the-art methods for PK prediction. This collection of methods allows a wide variety of data to be used for PK prediction. These methods are configured and data is specified in an intuitive user interface in which compound and PK data is entered using a familiar spreadsheet format. Predictions for compounds may be run in either single- or batch-mode. All models and scripts are delivered with the product, enabling you to inspect and modify the models to suit your particular research needs.