Products

ADME WorkBench

The shortest path from chemical properties and preclinical data to human ADME prediction

ADME Workbench is a versatile software application providing flexible, robust pharmacokinetic modeling by integrating state-of-the-art absorption, distribution, metabolism and excretion methods. Designed for research applications in toxicology, pharmacology and biotechnology, ADME Workbench supports pharmacokinetic prediction from in vitro and/or in vivo data for drugs and environmental

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acslX

The modeling, execution, and analysis environment for continuous dynamic systems and processes.

As the descendant of the ACSL family of modeling and simulation tools, originally developed in 1974 and now widely used for PBPK and PK/PD modeling, acslX supports both textual and graphical languages for specifying complex biological models, and a Matlab-like scripting language for specification of parameter estimation, sensitivity analysis, Monte-Carlo, or Markov-Chain Monte Carlo analyses. For computationally intensive problems, acslX includes support for cluster/grid computing.  Data integration capabilities with Microsoft Excel and Access are provided, and a PBPK/PK/PD toolkit is also available which includes linear and nonlinear PBPK models of various organs, exposure models for inhalation, oral and dermal exposures, and a variety of PD dose response models.

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